Eighteenth-century anatomist Dr. Thomas Silkstone travels to the English countryside to unravel a tangled web of mystery, medicine, and murder. A brilliant man of science, Dr. Thomas Silkstone is not one to heed superstition. But when he arrives at the estate of the lovely widow Lady Lydia Farrell, he finds that it's not just her grain and livestock at risk. A shroud of mystery surrounds Lydia's lost child, who may still be alive in a workhouse. A natural disaster fills the skies with smoke and ash, clogging the lungs of all who breathe it in. And the grisly details of a father's crime compel Dr. Silkstone to look for answers beyond his medical books�between the devil and the deep blue sea.